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PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome

The paraneoplastic Ma antigen (PNMA) genes are associated with cancer-induced paraneoplastic syndromes that present with neurological symptoms and autoantibody production. How PNMA proteins trigger a severe autoimmune disease is unclear. PNMA genes are predominately expressed in the central nervous...

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Detalles Bibliográficos
Autores principales: Xu, Junjie, Erlendsson, Simon, Singh, Manvendra, Regier, Matthew, Ibiricu, Iosune, Day, Gregory S., Piquet, Amanda L., Clardy, Stacey L., Feschotte, Cedric, Briggs, John A. G., Shepherd, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934673/
https://www.ncbi.nlm.nih.gov/pubmed/36798413
http://dx.doi.org/10.1101/2023.02.09.527862