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Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Protein-protein interactions (PPIs) regulate many cellular processes, and engineered PPIs have cell and gene therapy applications. Here we introduce massively parallel protein-protein interaction measurement by sequencing (MP3-seq), an easy-to-use and highly scalable yeast-two-hybrid approach for me...

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Detalles Bibliográficos
Autores principales: Baryshev, Alexander, La Fleur, Alyssa, Groves, Benjamin, Michel, Cirstyn, Baker, David, Ljubetič, Ajasja, Seelig, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934699/
https://www.ncbi.nlm.nih.gov/pubmed/36798377
http://dx.doi.org/10.1101/2023.02.08.527770