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P53 Acetylation Exerts Critical Roles In Pressure Overload Induced Coronary Microvascular Dysfunction and Heart Failure

Coronary microvascular dysfunction (CMD) has been shown to contribute to cardiac hypertrophy and heart failure with preserved ejection fraction. At this point, there are no proven treatments for CMD. We have shown that histone acetylation may play a critical role in the regulation of CMD. By using a...

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Detalles Bibliográficos
Autores principales: He, Xiaochen, Cantrell, Aubrey C, Williams, Quinesha A, Gu, Wei, Chen, Yingjie, Chen, Jian-Xiong, Zeng, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934706/
https://www.ncbi.nlm.nih.gov/pubmed/36798200
http://dx.doi.org/10.1101/2023.02.08.527691