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Recombinant FOXN1 fusion protein increases T cell generation in aged mice

BACKGROUND: Although the thymus continues to export T cells throughout life, it undergoes a profound involution/atrophy with age, resulting in decreased numbers of T cells in the older adult, which has direct etiological linkages with many diseases. T cell development in the thymus is dependent on t...

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Detalles Bibliográficos
Autores principales: Zhao, Jin, Zhang, Zhenzhen, Lai, Kuan Chen, Lai, Laijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934747/
https://www.ncbi.nlm.nih.gov/pubmed/36798162
http://dx.doi.org/10.21203/rs.3.rs-2557067/v1