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Incorporating data from multiple endpoints in the analysis of clinical trials: example from RSV vaccines

BACKGROUND: To achieve licensure, interventions typically must demonstrate efficacy against a primary outcome in a randomized clinical trial. However, selecting a single primary outcome a priori is challenging. Incorporating data from multiple and related outcomes might help to increase statistical...

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Detalles Bibliográficos
Autores principales: Prunas, Ottavia, Willemsen, Joukje E., Bont, Louis, Pitzer, Virginia E., Warren, Joshua L., Weinberger, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934779/
https://www.ncbi.nlm.nih.gov/pubmed/36798386
http://dx.doi.org/10.1101/2023.02.07.23285596