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Blocking muscle wasting via deletion of the muscle specific E3 ubiquitin ligase MuRF1 impedes pancreatic tumor growth

Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigated the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting induced by pancreatic cancer. Murine pancreatic cancer (KPC)...

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Detalles Bibliográficos
Autores principales: Neyroud, Daria, Laitano, Orlando, Daguspta, Aneesha, Lopez, Christopher, Schmitt, Rebecca E., Schneider, Jessica Z., Hammers, David W., Sweeney, H. Lee, Walter, Glenn A, Doles, Jason, Judge, Sarah M., Judge, Andrew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934780/
https://www.ncbi.nlm.nih.gov/pubmed/36798266
http://dx.doi.org/10.21203/rs.3.rs-2524562/v1