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Blocking muscle wasting via deletion of the muscle specific E3 ubiquitin ligase MuRF1 impedes pancreatic tumor growth
Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigated the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting induced by pancreatic cancer. Murine pancreatic cancer (KPC)...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934780/ https://www.ncbi.nlm.nih.gov/pubmed/36798266 http://dx.doi.org/10.21203/rs.3.rs-2524562/v1 |