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Lack of evidence for increased transcriptional noise in aged tissues

Aging is often associated with a loss of cell type identity that results in an increase in transcriptional noise in aged tissues. If this phenomenon reflects a fundamental property of aging remains an open question. Transcriptional changes at the cellular level are best detected by single-cell RNA s...

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Detalles Bibliográficos
Autores principales: Ibañez-Solé, Olga, Ascensión, Alex M, Araúzo-Bravo, Marcos J, Izeta, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934862/
https://www.ncbi.nlm.nih.gov/pubmed/36576247
http://dx.doi.org/10.7554/eLife.80380