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B cell receptor-induced IL-10 production from neonatal mouse CD19(+)CD43(-) cells depends on STAT5-mediated IL-6 secretion
Newborns are unable to reach the adult-level humoral immune response partly due to the potent immunoregulatory role of IL-10. Increased IL-10 production by neonatal B cells has been attributed to the larger population of IL-10-producting CD43(+) B-1 cells in neonates. Here, we show that neonatal mou...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934864/ https://www.ncbi.nlm.nih.gov/pubmed/36735294 http://dx.doi.org/10.7554/eLife.83561 |