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B cell receptor-induced IL-10 production from neonatal mouse CD19(+)CD43(-) cells depends on STAT5-mediated IL-6 secretion

Newborns are unable to reach the adult-level humoral immune response partly due to the potent immunoregulatory role of IL-10. Increased IL-10 production by neonatal B cells has been attributed to the larger population of IL-10-producting CD43(+) B-1 cells in neonates. Here, we show that neonatal mou...

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Detalles Bibliográficos
Autores principales:	Sakai, Jiro, Yang, Jiyeon, Chou, Chao-Kai, Wu, Wells W, Akkoyunlu, Mustafa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934864/ https://www.ncbi.nlm.nih.gov/pubmed/36735294 http://dx.doi.org/10.7554/eLife.83561

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