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Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor diversity

T cells play a crucial role in combatting SARS-CoV-2 and forming long-term memory responses to this coronavirus. The emergence of SARS-CoV-2 variants that can evade T cell immunity has raised concerns about vaccine efficacy and the risk of reinfection. Some SARS-CoV-2 T cell epitopes elicit clonally...

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Detalles Bibliográficos
Autores principales: Wu, Daichao, Efimov, Grigory A., Bogolyubova, Apollinariya V., Pierce, Brian G., Mariuzza, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934920/
https://www.ncbi.nlm.nih.gov/pubmed/36806685
http://dx.doi.org/10.1016/j.jbc.2023.103035