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Targeting BRAF V600E in metastatic colorectal cancer: where are we today?

Colorectal cancer (CRC) is the second most frequent cause of direct cancer death worldwide. The study of the molecular state of oncogenes has predictive and prognostic value in metastatic CRC (mCRC). The B-raf proto-oncogene (BRAF) gene mutation represents the 8%–12% of all mutations in mCRC. The BR...

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Detalles Bibliográficos
Autores principales: Guerrero, Rodrigo Motta, Labajos, Veronica Arnao, Ballena, Sophia Lozano, Macha, Carlos Aliaga, Lezama, Miguel Sotelo, Roman, Cristian Pacheco, Beltran, Paola Montenegro, Torrejon, Alejandro Figueroa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934973/
https://www.ncbi.nlm.nih.gov/pubmed/36819812
http://dx.doi.org/10.3332/ecancer.2022.1489