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Targeting BRAF V600E in metastatic colorectal cancer: where are we today?
Colorectal cancer (CRC) is the second most frequent cause of direct cancer death worldwide. The study of the molecular state of oncogenes has predictive and prognostic value in metastatic CRC (mCRC). The B-raf proto-oncogene (BRAF) gene mutation represents the 8%–12% of all mutations in mCRC. The BR...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934973/ https://www.ncbi.nlm.nih.gov/pubmed/36819812 http://dx.doi.org/10.3332/ecancer.2022.1489 |