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SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice

Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019 (COVID-19) syndrome, but its underlying mechanisms are not completely understood. Evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike protein or its fragments are released fro...

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Detalles Bibliográficos
Autores principales: Fontes-Dantas, Fabricia L., Fernandes, Gabriel G., Gutman, Elisa G., De Lima, Emanuelle V., Antonio, Leticia S., Hammerle, Mariana B., Mota-Araujo, Hannah P., Colodeti, Lilian C., Araújo, Suzana M.B., Froz, Gabrielle M., da Silva, Talita N., Duarte, Larissa A., Salvio, Andreza L., Pires, Karina L., Leon, Luciane A.A., Vasconcelos, Claudia Cristina F., Romão, Luciana, Savio, Luiz Eduardo B., Silva, Jerson L., da Costa, Robson, Clarke, Julia R., Da Poian, Andrea T., Alves-Leon, Soniza V., Passos, Giselle F., Figueiredo, Claudia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935273/
https://www.ncbi.nlm.nih.gov/pubmed/36857178
http://dx.doi.org/10.1016/j.celrep.2023.112189