Enzymatically amplified linear dbDNA(TM) as a rapid and scalable solution to industrial lentiviral vector manufacturing

Traditional bacterial fermentation techniques used to manufacture plasmid are time-consuming, expensive, and inherently unstable. The production of sufficient GMP grade material thus imposes a major bottleneck on industrial-scale manufacturing of lentiviral vectors (LVV). Touchlight’s linear doggybo...

Descripción completa

Detalles Bibliográficos
Autores principales: Barreira, Maria, Kerridge, Claire, Jorda, Sara, Olofsson, Didrik, Neumann, Alexander, Horton, Helen, Smith-Moore, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935383/
https://www.ncbi.nlm.nih.gov/pubmed/35606492
http://dx.doi.org/10.1038/s41434-022-00343-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935383/
https://www.ncbi.nlm.nih.gov/pubmed/35606492
http://dx.doi.org/10.1038/s41434-022-00343-4

Ejemplares similares