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Enzymatically amplified linear dbDNA(TM) as a rapid and scalable solution to industrial lentiviral vector manufacturing
Traditional bacterial fermentation techniques used to manufacture plasmid are time-consuming, expensive, and inherently unstable. The production of sufficient GMP grade material thus imposes a major bottleneck on industrial-scale manufacturing of lentiviral vectors (LVV). Touchlight’s linear doggybo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935383/ https://www.ncbi.nlm.nih.gov/pubmed/35606492 http://dx.doi.org/10.1038/s41434-022-00343-4 |