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Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling

Complex bidirectional cross talk between adipocytes and adipose tissue immune cells plays an important role in regulating adipose function, inflammation, and insulin responsiveness. Adipocytes secrete the pleiotropic cytokine IL-6 in response to both inflammatory and catabolic stimuli. Previous stud...

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Detalles Bibliográficos
Autores principales: Luan, Danny, Dadpey, Benyamin, Zaid, Jessica, Bridge-Comer, Pania E., DeLuca, Julia H., Xia, Wenmin, Castle, Joshua, Reilly, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935493/
https://www.ncbi.nlm.nih.gov/pubmed/36449000
http://dx.doi.org/10.2337/db22-0444