DPP-4 Inhibitor and Sulfonylurea Differentially Reverse Type 2 Diabetes–Induced Blood–Brain Barrier Leakage and Normalize Capillary Pericyte Coverage

Microvascular pathology in the brain is one of the suggested mechanisms underlying the increased incidence and progression of neurodegenerative diseases in people with type 2 diabetes (T2D). Although accumulating data suggest a neuroprotective effect of antidiabetics, the underlying mechanisms are u...

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Detalles Bibliográficos
Autores principales: Elabi, Osama F., Karampatsi, Dimitra, Vercalsteren, Ellen, Lietzau, Grazyna, Nyström, Thomas, Klein, Thomas, Darsalia, Vladimer, Patrone, Cesare, Paul, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935496/
https://www.ncbi.nlm.nih.gov/pubmed/36448982
http://dx.doi.org/10.2337/db22-0674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935496/
https://www.ncbi.nlm.nih.gov/pubmed/36448982
http://dx.doi.org/10.2337/db22-0674

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