i-Motif folding intermediates with zero-nucleotide loops are trapped by 2′-fluoroarabinocytidine via F···H and O···H hydrogen bonds

G-quadruplex and i-motif nucleic acid structures are believed to fold through kinetic partitioning mechanisms. Such mechanisms explain the structural heterogeneity of G-quadruplex metastable intermediates which have been extensively reported. On the other hand, i-motif folding is regarded as predict...

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Detalles Bibliográficos
Autores principales: El-Khoury, Roberto, Macaluso, Veronica, Hennecker, Christopher, Mittermaier, Anthony K., Orozco, Modesto, González, Carlos, Garavís, Miguel, Damha, Masad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935537/
https://www.ncbi.nlm.nih.gov/pubmed/36797370
http://dx.doi.org/10.1038/s42004-023-00831-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935537/
https://www.ncbi.nlm.nih.gov/pubmed/36797370
http://dx.doi.org/10.1038/s42004-023-00831-7

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