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Functional connectivity signatures of NMDAR dysfunction in schizophrenia—integrating findings from imaging genetics and pharmaco-fMRI

Both, pharmacological and genome-wide association studies suggest N-methyl-D-aspartate receptor (NMDAR) dysfunction and excitatory/inhibitory (E/I)-imbalance as a major pathophysiological mechanism of schizophrenia. The identification of shared fMRI brain signatures of genetically and pharmacologica...

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Detalles Bibliográficos
Autores principales: Gaebler, Arnim J., Fakour, Nilüfer, Stöhr, Felix, Zweerings, Jana, Taebi, Arezoo, Suslova, Mariia, Dukart, Juergen, Hipp, Joerg F., Adhikari, Bhim M., Kochunov, Peter, Muthukumaraswamy, Suresh D., Forsyth, Anna, Eggermann, Thomas, Kraft, Florian, Kurth, Ingo, Paulzen, Michael, Gründer, Gerhard, Schneider, Frank, Mathiak, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935542/
https://www.ncbi.nlm.nih.gov/pubmed/36797233
http://dx.doi.org/10.1038/s41398-023-02344-2