Cargando…

1′-O-methyl-averantin isolated from the endolichenic fungus Jackrogersella sp. EL001672 suppresses colorectal cancer stemness via sonic Hedgehog and Notch signaling

Endolichenic fungi are host organisms that live on lichens and produce a wide variety of secondary metabolites. Colorectal cancer stem cells are capable of self-renewal and differentiation into cancer cells, which makes cancers difficult to eradicate. New alternative therapeutics are needed to inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Varlı, Mücahit, Lee, Eun-Young, Yang, Yi, Zhou, Rui, Taş, İsa, Pulat, Sultan, Gamage, Chathurika D. B., Park, So-Yeon, Hur, Jae-Seoun, Nam, Sang-Jip, Kim, Hangun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935543/
https://www.ncbi.nlm.nih.gov/pubmed/36797277
http://dx.doi.org/10.1038/s41598-023-28773-z