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1′-O-methyl-averantin isolated from the endolichenic fungus Jackrogersella sp. EL001672 suppresses colorectal cancer stemness via sonic Hedgehog and Notch signaling
Endolichenic fungi are host organisms that live on lichens and produce a wide variety of secondary metabolites. Colorectal cancer stem cells are capable of self-renewal and differentiation into cancer cells, which makes cancers difficult to eradicate. New alternative therapeutics are needed to inhib...
Autores principales: | Varlı, Mücahit, Lee, Eun-Young, Yang, Yi, Zhou, Rui, Taş, İsa, Pulat, Sultan, Gamage, Chathurika D. B., Park, So-Yeon, Hur, Jae-Seoun, Nam, Sang-Jip, Kim, Hangun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935543/ https://www.ncbi.nlm.nih.gov/pubmed/36797277 http://dx.doi.org/10.1038/s41598-023-28773-z |
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