TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

Although radiotherapy can promote antitumour immunity, the mechanisms underlying this phenomenon remain unclear. Here, we demonstrate that the expression of the E3 ubiquitin ligase, tumour cell-intrinsic tripartite motif-containing 21 (TRIM21) in tumours, is inversely associated with the response to...

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Detalles Bibliográficos
Autores principales: Li, Jun-Yan, Zhao, Yin, Gong, Sha, Wang, Miao-Miao, Liu, Xu, He, Qing-Mei, Li, Ying-Qin, Huang, Sheng-Yan, Qiao, Han, Tan, Xi-Rong, Ye, Ming-Liang, Zhu, Xun-Hua, He, Shi-Wei, Li, Qian, Liang, Ye-Lin, Chen, Kai-Lin, Huang, Sai-Wei, Li, Qing-Jie, Ma, Jun, Liu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935546/
https://www.ncbi.nlm.nih.gov/pubmed/36797289
http://dx.doi.org/10.1038/s41467-023-36523-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935546/
https://www.ncbi.nlm.nih.gov/pubmed/36797289
http://dx.doi.org/10.1038/s41467-023-36523-y

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