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A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection

Bacteria can inhibit the growth of other bacteria by injecting effectors using a type VI secretion system (T6SS). T6SS effectors can also be injected into eukaryotic cells to facilitate bacterial survival, often by targeting the cytoskeleton. Here, we show that the trans-kingdom antimicrobial T6SS e...

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Detalles Bibliográficos
Autores principales: Sá-Pessoa, Joana, López-Montesino, Sara, Przybyszewska, Kornelia, Rodríguez-Escudero, Isabel, Marshall, Helina, Ova, Adelia, Schroeder, Gunnar N., Barabas, Peter, Molina, María, Curtis, Tim, Cid, Víctor J., Bengoechea, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935632/
https://www.ncbi.nlm.nih.gov/pubmed/36797302
http://dx.doi.org/10.1038/s41467-023-36629-3