A Multifunctional (-)-Meptazinol-Serotonin Hybrid Ameliorates Oxidative Stress-Associated Apoptotic Neuronal Death and Memory Deficits via Activating the Nrf2/Antioxidant Enzyme Pathway

The pathogenesis of Alzheimer's disease (AD) involves multiple pathophysiological processes. Oxidative stress is a major cause of AD-associated neuronal injury. The current research was designed to examine whether a novel (-)-meptazinol-serotonin hybrid (Mep-S) with potent antioxidant activity...

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Detalles Bibliográficos
Autores principales: Zhao, Faxue, Zhao, Lin, Zhou, Yan, Tan, Xiaofang, Yang, Yang, Ni, Wenwen, Zheng, Wei, Chen, Hongzhuan, Qiu, Yu, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935814/
https://www.ncbi.nlm.nih.gov/pubmed/36819782
http://dx.doi.org/10.1155/2023/6935947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935814/
https://www.ncbi.nlm.nih.gov/pubmed/36819782
http://dx.doi.org/10.1155/2023/6935947

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