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A Multifunctional (-)-Meptazinol-Serotonin Hybrid Ameliorates Oxidative Stress-Associated Apoptotic Neuronal Death and Memory Deficits via Activating the Nrf2/Antioxidant Enzyme Pathway
The pathogenesis of Alzheimer's disease (AD) involves multiple pathophysiological processes. Oxidative stress is a major cause of AD-associated neuronal injury. The current research was designed to examine whether a novel (-)-meptazinol-serotonin hybrid (Mep-S) with potent antioxidant activity...
Autores principales: | Zhao, Faxue, Zhao, Lin, Zhou, Yan, Tan, Xiaofang, Yang, Yang, Ni, Wenwen, Zheng, Wei, Chen, Hongzhuan, Qiu, Yu, Li, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935814/ https://www.ncbi.nlm.nih.gov/pubmed/36819782 http://dx.doi.org/10.1155/2023/6935947 |
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