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AAV- based vector improvements unrelated to capsid protein modification
Recombinant adeno-associated virus (rAAV) is the leading platform for delivering genetic constructs in vivo. To date, three AAV-based gene therapeutic agents have been approved by the FDA and are used in clinical practice. Despite the distinct advantages of gene therapy development, it is clear that...
Autores principales: | Shitik, Ekaterina M., Shalik, Igor K., Yudkin, Dmitry V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935841/ https://www.ncbi.nlm.nih.gov/pubmed/36817775 http://dx.doi.org/10.3389/fmed.2023.1106085 |
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