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Interleukin-35 -producing B cells rescues inflammatory bowel disease in a mouse model via STAT3 phosphorylation and intestinal microbiota modification

Interleukin-35 (IL-35)-producing B cells (IL-35(+)B cells) play an important role in diseases, and the expansion of IL-35(+) immune cells have been observed in inflammatory bowel disease (IBD). However, how IL-35(+)B cells function and the manner in which they perform their roles remain unclear. In...

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Detalles Bibliográficos
Autores principales: Xie, Minxiang, Zhu, Yuzhen, Zhou, Yunjiao, Wang, Qiao, Gu, Erli, Chu, Yiwei, Wang, Luman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935866/
https://www.ncbi.nlm.nih.gov/pubmed/36797242
http://dx.doi.org/10.1038/s41420-023-01366-5