The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics

Phosphatidylinositol (3,4,5) trisphosphate (PIP3) is a plasma membrane-bound signaling phospholipid involved in many cellular signaling pathways that control crucial cellular processes and behaviors, including cytoskeleton remodeling, metabolism, chemotaxis, and apoptosis. Therefore, defective PIP3...

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Detalles Bibliográficos
Autores principales: Wijayaratna, Dhanushan, Ratnayake, Kasun, Ubeysinghe, Sithurandi, Kankanamge, Dinesh, Tennakoon, Mithila, Karunarathne, Ajith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935898/
https://www.ncbi.nlm.nih.gov/pubmed/36797332
http://dx.doi.org/10.1038/s41598-023-29639-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935898/
https://www.ncbi.nlm.nih.gov/pubmed/36797332
http://dx.doi.org/10.1038/s41598-023-29639-0

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