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The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis
OBJECTIVES: The mammalian target of Rapamycin (mTOR) is a metabolic master regulator of both innate and adaptive immunity; however, its exact role in stromal cell biology is unknown. In this study we explored the role of the mTOR pathway on Rheumatoid Arthritis synovial fibroblast (RASF) metabolism...
Autores principales: | Barker, Brianne E., Hanlon, Megan M., Marzaioli, Viviana, Smith, Conor M., Cunningham, Clare C., Fletcher, Jean M., Veale, Douglas J., Fearon, Ursula, Canavan, Mary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936094/ https://www.ncbi.nlm.nih.gov/pubmed/36817783 http://dx.doi.org/10.3389/fmed.2023.1029021 |
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