AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation

The AurkA kinase is a well-known mitotic regulator, frequently overexpressed in tumors. The microtubule-binding protein TPX2 controls AurkA activity, localization, and stability in mitosis. Non-mitotic roles of AurkA are emerging, and increased nuclear localization in interphase has been correlated...

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Detalles Bibliográficos
Autores principales: Asteriti, Italia Anna, Polverino, Federica, Stagni, Venturina, Sterbini, Valentina, Ascanelli, Camilla, Naso, Francesco Davide, Mastrangelo, Anna, Rosa, Alessandro, Paiardini, Alessandro, Lindon, Catherine, Guarguaglini, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936162/
https://www.ncbi.nlm.nih.gov/pubmed/36797043
http://dx.doi.org/10.26508/lsa.202201726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936162/
https://www.ncbi.nlm.nih.gov/pubmed/36797043
http://dx.doi.org/10.26508/lsa.202201726

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