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Remodelling of the fibre-aggregate structure of collagen gels by cancer-associated fibroblasts: A time-resolved grey-tone image analysis based on stochastic modelling

INTRODUCTION: Solid tumors consist of tumor cells associated with stromal and immune cells, secreted factors and extracellular matrix (ECM), which together constitute the tumor microenvironment. Among stromal cells, activated fibroblasts, known as cancer-associated fibroblasts (CAFs) are of particul...

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Detalles Bibliográficos
Autores principales: Gommes, Cedric J., Louis, Thomas, Bourgot, Isabelle, Noël, Agnès, Blacher, Silvia, Maquoi, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936192/
https://www.ncbi.nlm.nih.gov/pubmed/36818478
http://dx.doi.org/10.3389/fimmu.2022.988502