In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals

Since initial regulatory action in 2010 in Canada, bisphenol A (BPA) has been progressively replaced by structurally related alternative chemicals. Unfortunately, many of these chemicals are data-poor, limiting toxicological risk assessment. We used high-throughput transcriptomics to evaluate potent...

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Detalles Bibliográficos
Autores principales: Matteo, Geronimo, Leingartner, Karen, Rowan-Carroll, Andrea, Meier, Matthew, Williams, Andrew, Beal, Marc A, Gagné, Matthew, Farmahin, Reza, Wickramasuriya, Shamika, Reardon, Anthony J F, Barton-Maclaren, Tara, Christopher Corton, J, Yauk, Carole L, Atlas, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Endocrine Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936204/
https://www.ncbi.nlm.nih.gov/pubmed/36534918
http://dx.doi.org/10.1093/toxsci/kfac127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936204/
https://www.ncbi.nlm.nih.gov/pubmed/36534918
http://dx.doi.org/10.1093/toxsci/kfac127

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