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Shikonin improves pulmonary vascular remodeling in monocrotaline‑induced pulmonary arterial hypertension via regulation of PKM2

Pulmonary arterial hypertension (PAH), a fatal disease with an insidious onset and rapid progression, shows characteristics such as increases in pulmonary circulatory resistance and pulmonary arterial pressure, and progressive right heart failure. Shikonin can reduce right ventricular systolic press...

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Detalles Bibliográficos
Autores principales: Li, Wenfeng, Chen, Wenjuan, Peng, Hongyan, Xiao, Zhenghui, Liu, Jinqiao, Zeng, Yunhong, Huang, Ting, Song, Qingqing, Wang, Xun, Xiao, Yunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936259/
https://www.ncbi.nlm.nih.gov/pubmed/36734266
http://dx.doi.org/10.3892/mmr.2023.12947