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Evolutive emergence and divergence of an Ig regulatory node: An environmental sensor getting cues from the aryl hydrocarbon receptor?

One gene, the immunoglobulin heavy chain (IgH) gene, is responsible for the expression of all the different antibody isotypes. Transcriptional regulation of the IgH gene is complex and involves several regulatory elements including a large element at the 3’ end of the IgH gene locus (3’RR). Animal m...

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Detalles Bibliográficos
Autores principales: D'Addabbo, Pietro, Frezza, Domenico, Sulentic, Courtney E.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936319/
https://www.ncbi.nlm.nih.gov/pubmed/36817426
http://dx.doi.org/10.3389/fimmu.2023.996119