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Computational analysis of the sequence-structure relation in SARS-CoV-2 spike protein using protein contact networks

The structure of proteins impacts directly on the function they perform. Mutations in the primary sequence can provoke structural changes with consequent modification of functional properties. SARS-CoV-2 proteins have been extensively studied during the pandemic. This wide dataset, related to sequen...

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Detalles Bibliográficos
Autores principales: Guzzi, Pietro Hiram, di Paola, Luisa, Puccio, Barbara, Lomoio, Ugo, Giuliani, Alessandro, Veltri, Pierangelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936485/
https://www.ncbi.nlm.nih.gov/pubmed/36808182
http://dx.doi.org/10.1038/s41598-023-30052-w