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STING as an emerging therapeutic target for drug discovery: Perspectives from the global patent landscape

BACKGROUND: The STimulator of INterferon Genes (STING) plays an essential role in the innate immune system by inducing the expression of type I interferons (IFNs) and inflammatory cytokines upon sensing cytosolic DNA. Although modulating STING has shown promise as a potential treatment for cancers a...

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Detalles Bibliográficos
Autores principales: Kong, Xiangjun, Zuo, Huali, Huang, Hsien-Da, Zhang, Qianru, Chen, Jiayu, He, Chengwei, Hu, Yuanjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936525/
https://www.ncbi.nlm.nih.gov/pubmed/35636721
http://dx.doi.org/10.1016/j.jare.2022.05.006