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Lung specific homing of diphenyleneiodonium chloride improves pulmonary fibrosis by inhibiting macrophage M2 metabolic program

INTRODUCTION: Pulmonary fibrosis (PF) is a fatal disease with a variable and unpredictable course. Effective clinical treatment for PF remains a challenge due to low drug accumulation in lungs and imbalanced polarization of pro/anti-fibrotic macrophages. OBJECTIVES: To identify the alteration of imm...

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Detalles Bibliográficos
Autores principales: Wang, Huirui, Gao, Yinghui, Wang, Li, Yu, Yang, Zhang, Jiaozhen, Liu, Chunyu, Song, Yaxin, Xu, Haochuan, Wang, Jingcheng, Lou, Hongxiang, Dong, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936526/
https://www.ncbi.nlm.nih.gov/pubmed/36725191
http://dx.doi.org/10.1016/j.jare.2022.04.012