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Amyloid Fibers of α-Synuclein Catalyze Chemical Reactions
[Image: see text] Amyloid fibers of the protein α-synuclein, found in Lewy body deposits, are hallmarks of Parkinson’s disease. We here show that α-synuclein amyloids catalyze biologically relevant chemical reactions in vitro. Amyloid fibers, but not monomers, of α-synuclein catalyzed hydrolysis of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936539/ https://www.ncbi.nlm.nih.gov/pubmed/36745416 http://dx.doi.org/10.1021/acschemneuro.2c00799 |