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Amyloid Fibers of α-Synuclein Catalyze Chemical Reactions

[Image: see text] Amyloid fibers of the protein α-synuclein, found in Lewy body deposits, are hallmarks of Parkinson’s disease. We here show that α-synuclein amyloids catalyze biologically relevant chemical reactions in vitro. Amyloid fibers, but not monomers, of α-synuclein catalyzed hydrolysis of...

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Detalles Bibliográficos
Autores principales:	Horvath, Istvan, Wittung-Stafshede, Pernilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936539/ https://www.ncbi.nlm.nih.gov/pubmed/36745416 http://dx.doi.org/10.1021/acschemneuro.2c00799

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