Cargando…

Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography–High-Resolution Mass Spectrometry

[Image: see text] Orexin-A (OXA) and -B (OXB) are involved in the regulation of multiple physiological functions including the sleep–wake states; therefore, it is critical to monitor their levels under various conditions. Unfortunately, the widely used radioimmunoassay has insufficient specificity f...

Descripción completa

Detalles Bibliográficos
Autores principales: Narita, Naohiro, Yamada, Ryuji, Kakehi, Masaaki, Kimura, Haruhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936545/
https://www.ncbi.nlm.nih.gov/pubmed/36719857
http://dx.doi.org/10.1021/acschemneuro.2c00370