Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C–H Oxyfunctionalization Reactions

[Image: see text] The generation of enantiodivergent biocatalysts for C–H oxyfunctionalizations is ever more important in modern synthetic chemistry. Here, we have applied the FuncLib algorithm based on phylogenetic and Rosetta calculations to design a diverse repertoire of active, stable, and enant...

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Detalles Bibliográficos
Autores principales: Gomez de Santos, Patricia, Mateljak, Ivan, Hoang, Manh Dat, Fleishman, Sarel J., Hollmann, Frank, Alcalde, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936548/
https://www.ncbi.nlm.nih.gov/pubmed/36689349
http://dx.doi.org/10.1021/jacs.2c11118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936548/
https://www.ncbi.nlm.nih.gov/pubmed/36689349
http://dx.doi.org/10.1021/jacs.2c11118

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