pH-Dependent Capping Interactions Induce Large-Scale Structural Transitions in i-Motifs

[Image: see text] We study here a DNA oligonucleotide having the ability to form two different i-motif structures whose relative stability depends on pH and temperature. The major species at neutral pH is stabilized by two C:C(+) base pairs capped by two minor groove G:C:G:C tetrads. The high pH and...

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Detalles Bibliográficos
Autores principales: Serrano-Chacón, Israel, Mir, Bartomeu, Cupellini, Lorenzo, Colizzi, Francesco, Orozco, Modesto, Escaja, Núria, González, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936585/
https://www.ncbi.nlm.nih.gov/pubmed/36745195
http://dx.doi.org/10.1021/jacs.2c13043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936585/
https://www.ncbi.nlm.nih.gov/pubmed/36745195
http://dx.doi.org/10.1021/jacs.2c13043

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