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pH-Dependent Capping Interactions Induce Large-Scale Structural Transitions in i-Motifs
[Image: see text] We study here a DNA oligonucleotide having the ability to form two different i-motif structures whose relative stability depends on pH and temperature. The major species at neutral pH is stabilized by two C:C(+) base pairs capped by two minor groove G:C:G:C tetrads. The high pH and...
Autores principales: | Serrano-Chacón, Israel, Mir, Bartomeu, Cupellini, Lorenzo, Colizzi, Francesco, Orozco, Modesto, Escaja, Núria, González, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936585/ https://www.ncbi.nlm.nih.gov/pubmed/36745195 http://dx.doi.org/10.1021/jacs.2c13043 |
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