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An Enantiospecific Synthesis of Isoneoamphilectane Confirms Its Strained Tricyclic Structure

[Image: see text] We describe a total synthesis of the rare isocyanoterpene natural product isoneoamphilectane and two of its unnatural diastereomers. The significantly strained ring system of the reported natural product—along with a hypothesis about a biosynthetic relationship to related family me...

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Detalles Bibliográficos
Autores principales: Dwulet, Natalie C., Chahine, Zeinab, Le Roch, Karine G., Vanderwal, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936588/
https://www.ncbi.nlm.nih.gov/pubmed/36730688
http://dx.doi.org/10.1021/jacs.2c13137