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Single-cell heterogeneity and dynamic evolution of Ph-like acute lymphoblastic leukemia patient with novel TPR-PDGFRB fusion gene

Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a refractory and recurrent subtype of B-cell ALL enriched with kinase-activating rearrangements. Incomplete understanding of the heterogeneity within the tumor cells presents a major challenge for the diagnosis and therapy of...

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Detalles Bibliográficos
Autores principales: Zhang, Xuehong, Hou, Zhijie, Huang, Dan, Wang, Furong, Gao, Beibei, Zhang, Chengtao, Zhou, Dong, Lou, Jiacheng, Wang, Haina, Gao, Yuan, Kang, Zhijie, Lu, Ying, Liu, Quentin, Yan, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936632/
https://www.ncbi.nlm.nih.gov/pubmed/36797781
http://dx.doi.org/10.1186/s40164-023-00380-8