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Expression of substance P, neurokinin 1 receptor, Ki-67 and pyruvate kinase M2 in hormone receptor negative breast cancer and evaluation of impact on overall survival

BACKGROUND: Chronic inflammation is a hallmark of cancer, and it can be stimulated by many factors. Substance P (SP), through binding to neurokinin 1 receptor (NK1R), and pyruvate kinase M2 (PKM2) play critical roles in cancer development and progression via modulating the tumor microenvironment. Th...

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Detalles Bibliográficos
Autores principales: Al-Keilani, Maha S., Bdeir, Roba, Elstaty, Rana I., Alqudah, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936699/
https://www.ncbi.nlm.nih.gov/pubmed/36797689
http://dx.doi.org/10.1186/s12885-023-10633-8