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The transgenic IG-DMR sequence of the mouse Dlk1-Dio3 domain acquired imprinted DNA methylation during the post-fertilization period

BACKGROUND: Allele-specific methylation of the imprinting control region (ICR) is the molecular basis for the genomic imprinting phenomenon that is unique to placental mammals. We previously showed that the ICR at the mouse H19 gene locus (H19 ICR) was unexpectedly established after fertilization an...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Hitomi, Sugihara, Shokichi, Tanimoto, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936741/
https://www.ncbi.nlm.nih.gov/pubmed/36797774
http://dx.doi.org/10.1186/s13072-023-00482-x