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Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition
LINE-1 (L1) elements are a class of transposons, comprising approximately 19% and 21% of the mouse and human genomes, respectively. L1 retrotransposons can reverse transcribe their own RNA sequence into a de novo DNA copy integrated into a new genomic location. This activity, known as retrotransposi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Brasileira de Genética
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936793/ https://www.ncbi.nlm.nih.gov/pubmed/36734369 http://dx.doi.org/10.1590/1678-4685-GMB-2022-0268 |