Cargando…

MUC16 and TP53 family co-regulate tumor-stromal heterogeneity in pancreatic adenocarcinoma

MUC16/CA125 is one of the few oldest cancer biomarkers still used in current clinical practice. As mesothelium is an abundant source of MUC16 and a major contributor to stromal heterogeneity in PDAC, we investigated the regulation of MUC16 in tumor and stromal compartments individually. The trajecto...

Descripción completa

Detalles Bibliográficos
Autores principales: Chirravuri-Venkata, Ramakanth, Dam, Vi, Nimmakayala, Rama Krishna, Alsafwani, Zahraa Wajih, Bhyravbhatla, Namita, Lakshmanan, Imayavaramban, Ponnusamy, Moorthy P., Kumar, Sushil, Jain, Maneesh, Ghersi, Dario, Batra, Surinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936860/
https://www.ncbi.nlm.nih.gov/pubmed/36816942
http://dx.doi.org/10.3389/fonc.2023.1073820