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MUC16 and TP53 family co-regulate tumor-stromal heterogeneity in pancreatic adenocarcinoma
MUC16/CA125 is one of the few oldest cancer biomarkers still used in current clinical practice. As mesothelium is an abundant source of MUC16 and a major contributor to stromal heterogeneity in PDAC, we investigated the regulation of MUC16 in tumor and stromal compartments individually. The trajecto...
Autores principales: | Chirravuri-Venkata, Ramakanth, Dam, Vi, Nimmakayala, Rama Krishna, Alsafwani, Zahraa Wajih, Bhyravbhatla, Namita, Lakshmanan, Imayavaramban, Ponnusamy, Moorthy P., Kumar, Sushil, Jain, Maneesh, Ghersi, Dario, Batra, Surinder K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936860/ https://www.ncbi.nlm.nih.gov/pubmed/36816942 http://dx.doi.org/10.3389/fonc.2023.1073820 |
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